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Pestology Blog
Cockroach Baiting Efficacy and New Methods for Fighting Against Zoonotic Disease Transmission
Fairfax, VA – May 1, 2026
In this month's episode, the team doubles down on cockroach baiting research, covering two papers that uncover surprising details surrounding the efficacy of gel baits against American cockroaches and German cockroaches. They also review a cool new paper that outlines an outside the box approach to curbing zoonotic disease transmission in bats. We're joined by our NPMA's Chief Operating Officer, Andy Architect!
Featured Article Summaries
American Cockroaches and Gel Baits
The Influence of Competitive Food on the Performance of Several Insecticidal Gel Baits Against Different Life Stages of the American Cockroach (Blattodea: Blattidae)
The American cockroach is one of the most persistent urban pests. It creeps through sewer systems, invades restaurants and pantries, and even carries pathogens that pose real public health risks. Pest control professionals have long relied on insecticidal gel baits to manage infestations. But most bait research has focused on the German cockroach, the smaller indoor species that plagues apartment buildings and kitchens across the United States. The American cockroach is a larger, hardier, peridomestic species that has received far less attention. More critically, almost no research had examined how commercial gel baits perform against different life stages of the American cockroach when food is already available nearby.
That last detail matters. In the environments where American cockroaches thrive such as restaurants, warehouses, sewers, grocery stores, there is almost always competing food around. If a cockroach can choose between a piece of dog food and a gel bait, what does it choose? And does that choice vary depending on whether the cockroach is a young nymph or a full-grown adult? These were the questions researchers at the Auburn University set out to answer.
The researchers tested eleven commercial gel bait products against five distinct life stages of the American cockroach: small nymphs (1st–2nd instar), medium nymphs (3rd–4th instar), large nymphs (5th–6th instar), and adult males and females. Groups of ten cockroaches were placed in sealed glass jars containing a cardboard harborage, a water source, and approximately half a gram of gel bait. In one set of trials, a competing food source (a piece of dry dog food) was included to simulate a real-world environment with competing food. In another experiment, no competing food was provided, only giving cockroaches the bait as a food source.
Mortality was recorded every twelve hours for the first four days, then daily for fourteen days. The team tracked not just final death counts but also median survival time (MST) which was defined as the point at which half the cockroach population had died. This allowed the researchers to measure how fast each bait worked.
What they found was that Fipronil-based baits dominated. Combat Max (0.01% fipronil) and Max Force FC Magnum (0.05% fipronil) stood out from the pack. Both achieved greater than 95% mortality across all life stages and did so quickly with median survival times of just 24 to 72 hours, regardless of whether competing food was present. No other bait formulation came close to matching this consistency.
Interestingly, Dinotefuran-based baits struggled against young cockroaches. When competitive food was present, both products caused less than 50% mortality in small and medium nymphs over the full fourteen-day period. Even when food was removed, these baits failed to reliably kill early-stage nymphs. Their median survival times frequently could not even be calculated because fewer than half the test cockroaches had died by the end of the study.
These data showed that food availability dramatically changes the odds. For most products, removing competitive food improved outcomes significantly. Baits that produced only moderate results with food present saw mortality rates jump to 90% or higher once food was eliminated. Young cockroaches also presented a different challenge. Small and medium nymphs consistently survived longer and showed lower mortality rates than adults across nearly all bait types. This is likely due to behavioral factors associated with young nymphs since they are highly aggregative and spend more time sheltering inside harborages, meaning they encounter bait less frequently.
For me, this study showed that first, not all baits are equal and active ingredient matters. Second, when it comes to the American cockroach, sanitation genuinely matters. In environments where alternative food is readily available, cockroaches simply don't need to eat the bait, and many won't consume enough to reach a lethal dose. Lastly, prepare to account for life stage. A control program that achieves excellent results against adult cockroaches may leave large numbers of nymphs alive to eventually replenish the population. Rotating bait formulations, placing bait strategically near harborage areas, and targeting multiple life stages simultaneously could yield better control results against the American cockroach.
Article by Mike Bentley, PhD, BCE
References
Ashmita Sapkota, Arthur G Appel, The influence of competitive food on the performance of several insecticidal gel baits against different life stages of the American cockroach (Blattodea: Blattidae), Journal of Economic Entomology, 2026;, toag081, https://doi.org/10.1093/jee/toag081
German Cockroach Gel Baits
Behavioral Responses of German Cockroaches (Blattella Germanica l.) to Gel Baits under Varying Environmental Conditions
German cockroaches need little introduction. They are among the most common pests and can be difficult to control. They are often controlled using baits. We know that baits are very effective at killing cockroaches in the lab, very safe for the environment and people, and can even be effective by second hand as mortality from when one cockroach may eat another that has ingested the bait and then die itself. We know baits remain stable for at least 6 months without reapplication so the next question became, how well can the cockroaches find the bait. Other studies suggested that cockroaches may not be sniffing them out from far away, so the researchers put the idea to the test. How will they respond to gel baits in normal environments. Will they be able to find them?
There were a few different experiments they ran to explore these questions. For the experiments they used advion cockroach gel bait and maxforce fc magnum bait gel.
They set up arenas using kiddie pools with an egg carton harborage for the roaches that has water and regular food.
50 adult male cockroaches were put in each arena and allowed to acclimate for a week. Then they introduced the sticky card traps with baits. They checked how many individuals were stuck on the traps trying to get to the bait on a daily basis for a week. They did this design with the traps placed 30cm from the harborage and again with the traps placed 8cm from the harborage.
Then they did the whole thing again where they removed the food and water from the harborage for 48 hours and saw if that affected how many cockroaches were caught by the bait. They also tried it where they reduced the size of the harborage to simulate crowded conditions and see if that changed anything.
On top of those variety of experiments, they did the whole thing without the sticky cards and instead just allowed the cockroaches to feed on the bait and then assessed the mortality of the colony.
They generally found that the cockroaches didn’t go find baits further than 8cm away. Even those close by traps, didn’t show a significant difference between baited or unbaited control. However, there was a significant increase in mortality with these close baits when placed without the traps. This implies that the baits don’t attract the cockroaches when in an environment with limited air flow. But the close by baits might just be more likely to be encountered by cockroaches that don’t have to go far from their cozy harborage.
In the experiments where they removed the food and water, there was also no significant difference between the trap catches with bait or no bait. However, more cockroaches overall were caught and were killed by the baits when food and water were removed meaning that they got more daring and explored more when they were in need of food and water.
This highlights how important it is to remove food and water sources for cockroach populations as it can force them to explore more and eventually find more baits.
As for what this means for bait application, getting the bait as close as possible to the harborage is critical. It may also mean that adding attractants to the baits can be helpful in hitting more of the population.
Ellie Sanders, MS, BCE
Lucero, I.M., Porras-Villamil, J.F., Blevins, H., Lopina, A., Gaire, S. and DeVries, Z.C. (2026), Behavioral responses of German cockroaches (Blattella germanica L.) to gel baits under varying environmental conditions. Pest Manag Sci. https://doi.org/10.1002/ps.70694
Mosquito Vaccines
Ecological Vaccination: A Strategy to Prevent Zoonotic Spillover from Bats
Mosquitoes are well known for their ability to transmit diseases. But what if we had the ability to turn the tables? What if mosquitoes were the ones responsible for preventing disease in the first place? That’s what a group of scientists set to find out, specifically looking at the potential for using mosquitoes to vaccinate bats from disease, thus lessening the potential for bat-based disease transmission.
Bats are an excellent candidate for potential mosquito-based vaccine targeting, as they are well-known for harboring pathogens that have caused several “spillover” events into humans, such as COVID-19. However, the usual methods of vaccination are difficult to implement in wild bats. The usual ways of deploying a vaccine, such as intramuscular injections, oral baits, or topical applications are impractical and difficult to scale up. Therefore, the need to determine a means of vaccination that could be aligned with ecological interactions was paramount.
Enter, the humble Yellow Fever mosquito, also known as Aedes aegypti. Or, more accurately, a genetically modified version of Aedes aegypti that featured an insertion of a gene. This gene held the code for a live vaccine based on an arbovirus, which is a common type of virus that is found in both insects and mammals. The researchers designed two types of genes for this study: one that coded for a live vaccine of rabies, and one that coded for a live vaccine of Nipah virus, which is another dangerous and common disease that is transmitted by bats.
The researchers then took the vaccine-ladened mosquitoes and exposed them to rodents and bats in the lab. The rodents and bats were either fed the mosquitoes, or were exposed to bites from the mosquitoes. They then exposed the rodents and bats to the disease in question, again, either Rabies or Nipah virus, and examined the survival and the responses of their immune systems.
For both bats and rodents, and for both diseases, the researchers found an increase in the immune response and a higher rate of survival for individuals that interacted with the vaccine-bearing mosquitoes. This means that both ingestion of the vaccine-bearing mosquitoes or being bit by a vaccine-bearing mosquito confers protection against potential zoological disease threats. And, more importantly, bats are known to eat mosquitoes, and mosquitoes are known to feed on bats for a bloodmeal, meaning that both avenues are valid ecological interactions that could confer protection against zoonotic diseases.
But that was just in the lab- could these practices translate to the wild? In a controlled room that simulated a cave, the researchers released six bats from two species along with the vaccine-ladened mosquitoes and saw the same results- the bats had an increase in their immune response simply due to the association of the vaccine-ladened mosquitoes in the same area.
In addition to the vaccine-mosquitoes, the researchers also developed another means of vaccine deployment to bats: a saline trap. Bats, much like other mammals, need minerals to survive. Using a mist generator that released saline to attract the bats to the area, the researchers then were able to create a vaccine that was stable in a saline solution, which the bats lapped up happily. The researchers were able to show that these saline traps were also extremely effective at producing an immune response- this time against SARS CoV, or more commonly known as Covid.
Who knew disease control could be as simple as a bat feeding on a mosquito, taking a drink, or even being bit by a mosquito? With this trifecta effect that takes advantage of regular bat behavior, we could have a real means of zoonotic disease control on our hands. All of these options are much easier to scale up and deploy, which means not only less chance of diseases spreading across species, but also provides an opportunity to be able to tackle a zoonotic disease outbreak more quickly and effectively.
Article by Laura Rosenwald, BCE
References
Hongyue Li et al Ecological vaccination: A strategy to prevent zoonotic spillover from bats.Sci. Adv.12,eaec0269(2026).DOI:10.1126/sciadv.aec0269
Listen to the Episode!
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